Functional modules
HumanBase applies community detection to find cohesive gene clusters from a provided gene list and a selected relevant tissue. Genes within a cluster share local network neighborhoods and together form a cohesive, specific functional module.
Gene function prediction
Module detection enables systematic association of genes - even functionally uncharacterized genes - to specific processes and phenotypes represented in the detected modules.
Tissue-specific
Functional modules are identified with tissue-specific networks, which predict gene interactions from massive data collections. Thus the discovered modules potentially capture higher-order tissue-specific function.
